44 research outputs found

    Extending Scojo-PECT by migration based on system-level checkpointing

    Get PDF
    In recent years, a significant amount of research has been done on job scheduling in high performance computing area. Parallel jobs have different running time and require a different number of processors, thus jobs need to be scheduled and packed to improve system utilization. Scojo-PECT is a job scheduler which provides service guarantees by using coarse-grain time sharing. However, Scojo-PECT does not provide process migration. We extend the Scojo-PECT by migrating parallel jobs based on system-level checkpointing. We investigate different cases in the Scojo-PECT scheduling algorithm where migration based on system-level checkpointing can be used to improve resource utilization and reduce job response time. Our experimental results show reduction of relative response times on medium jobs over the results of the original Scojo-PECT scheduler and the long jobs do not suffer any disadvantage

    The Immungenicity and Cross-Neutralizing Activity of Enterovirus 71 Vaccine Candidate Strains

    Get PDF
    This study aimed to evaluate enterovirus 71 (EV-A71) vaccine candidate strains, including their genotypes, immunogenicity and cross-neutralization capacity. From clinical samples, EV-A71 strains were separated by using Vero cells. Six strains were chosen for vaccine candidates, and the sequences were analyzed. To detect the immunogenicity of the strains, we used them to immunize NIH mice at 0 and 14 days. Cytopathic effects (CPE) were examined to determine the EV-A71 neutralizing antibody (NTAb) titer 14 d after the first and second inoculations. To evaluate the cross-neutralizing capacity of the EV-A71 vaccine candidate strains, we tested serum immunized mice with ten EV-A71 genotype strains. Six EV-A71 vaccine candidate strains were identified, all belonging to sub-genotype C4, the prevalent genotype in China. The sequence similarity of the VP1 regions of the six candidate vaccine strains and three approved inactivated vaccines was 97.58%–97.77%, and the VP1 amino acid similarity was 98.65%–99.33%. Experiments were performed to evaluate the immunogenicity and cross-neutralizing activity of the EV-A71 vaccine candidate strains. The strains had good immunogenicity 14 d after two immunizations, inducing an NTAb titer ranging from 1:94 to 1:346. The NTAb seroconversion rates 14 d after one immunization were above 80% (except HB0007), and significantly increased immunogenicity of EV-A71 strains was observed post-inoculation. Furthermore, our candidate vaccine strains had broad cross-neutralizing activity after challenge with ten sub-genotypes of EV-A71. The highest NTAb titer/lowest NTAb titer ratios of sera against EV-A71 sub-genotypes were 8.0 (JS0002), 8.0 (JS0005), 21.3 (HB0005), 21.3 (HB0007), 10.7 (HB0040) and 8.0 (GD0002), respectively. Our EV-A71 strains had good immunogenicity and cross-neutralization activity, and have the potential to serve as vaccine strains for multivalent hand, foot and mouth disease vaccines

    Allelopathic effects of Ulva pertusa, Corallina pilulifera and Sargassum thunbergii on the growth of the dinoflagellates Heterosigma akashiwo and Alexandrium tamarense

    Get PDF
    The allelopathic effects of fresh tissue, dry powder and aqueous extracts of three macroalgae, Ulva pertusa, Corallina pilulifera and Sargassum thunbergii, on the growth of the dinoflagellates Heterosigma akashiwo and Alexandrium tamarense were evaluated using coexistence culture systems in which concentrations of the three macroalga were varied. The results of the coexistence assay showed that the growth of the two microalgae was strongly inhibited by using fresh tissue, dry powder and aqueous extracts of the three macroalga; the allelochemicals were lethal to H. akashiwo at relatively higher concentrations of the three macroalga. The macroalgae showing the most allelopathic effect on H. akashiwo and A. tamarense using fresh tissue were U. pertusa and S. thunbergii, using dry powder were S. thunbergii and U. pertusa, and using aqueous extracts were U. pertusa and C. pilulifera. We also examined the potential allelopathic effect on the two microalgae of culture filtrate of the three macroalga; culture medium filtrate initially exhibited no inhibitory effects when first added but inhibitory effects became apparent under semi-continuous addition, which suggested that continuous release of small quantities of rapidly degradable allelochemicals from the fresh macroalgal tissue were essential to effectively inhibit the growth of the two microalgae

    Evolution of Residual Stresses in Micro-arc Oxidation Ceramic Coatings on 6061 Al Alloy

    No full text
    Most researches on micro-arc oxidation mainly focus on the application rather than discovering the evolution of residual stresses. However, residual stresses in the surface coatings of structural components have adverse effects on their properties, such as fatigue life, dimensional stability and corrosion resistance, etc. The micro-arc oxidation ceramic coatings are produced on the surfaces of 6061 aluminum alloy by a homemade asymmetric AC type of micro-arc oxidation equipment of 20 kW. A constant current density of 4.4 +/- 0.1 A/dm(2) and a self-regulated composite electrolyte are used. The micro-arc oxidation treatment period ranges from 10 min to 40 min, and the thickness of the ceramic coatings is more than 20 mu m. Residual stresses attributed to gamma-Al2O3 constituent in the coatings at different micro-arc oxidation periods are analyzed by an X-ray diffractometer using the sin(2)psi method. The analysis results show that the residual stress in the ceramic coatings is compressive in nature, and it increases first and then decreases with micro-arc oxidation time increase. The maximum stress value is 1 667 +/- 20 MPa for period of 20 min Through analyzing the coating thickness, surface morphology and phase composition, it is found that the residual stress in the ceramic coatings is linked closely with the coating growth, the phase composition and the micro cracks formed. It is also found that both the heat treatment and the ultrasonic action release remarkably the residual compressive stress. The heat treatment makes the residual compressive stress value decrease 1 378 MPa. The ultrasonic action even alters the nature of the residual stress, making the residual compressive stress change into a residual tensile stress

    Evolution of Residual Stresses in Micro-arc Oxidation Ceramic Coatings on 6061 Al Alloy

    No full text
    Most researches on micro-arc oxidation mainly focus on the application rather than discovering the evolution of residual stresses. However, residual stresses in the surface coatings of structural components have adverse effects on their properties, such as fatigue life, dimensional stability and corrosion resistance, etc. The micro-arc oxidation ceramic coatings are produced on the surfaces of 6061 aluminum alloy by a homemade asymmetric AC type of micro-arc oxidation equipment of 20 kW. A constant current density of 4.4 +/- 0.1 A/dm(2) and a self-regulated composite electrolyte are used. The micro-arc oxidation treatment period ranges from 10 min to 40 min, and the thickness of the ceramic coatings is more than 20 mu m. Residual stresses attributed to gamma-Al2O3 constituent in the coatings at different micro-arc oxidation periods are analyzed by an X-ray diffractometer using the sin(2)psi method. The analysis results show that the residual stress in the ceramic coatings is compressive in nature, and it increases first and then decreases with micro-arc oxidation time increase. The maximum stress value is 1 667 +/- 20 MPa for period of 20 min Through analyzing the coating thickness, surface morphology and phase composition, it is found that the residual stress in the ceramic coatings is linked closely with the coating growth, the phase composition and the micro cracks formed. It is also found that both the heat treatment and the ultrasonic action release remarkably the residual compressive stress. The heat treatment makes the residual compressive stress value decrease 1 378 MPa. The ultrasonic action even alters the nature of the residual stress, making the residual compressive stress change into a residual tensile stress

    Ultrasonic gas flow metering in hydrogen-mixed natural gas using Lamb waves

    No full text
    Hydrogen mixing in existing natural gas pipelines efficiently achieves large-scale, long-distance, and low-cost hydrogen delivery. The physical properties of hydrogen and natural gas differ significantly. Hydrogen-mixed natural gas modifies the flow state and thermodynamic properties of the original natural gas in the pipeline. Hydrogen-mixed natural gas can lead to increased errors in ultrasonic flow metering because of the high sound speed and low density of hydrogen. Ultrasonic flowmeter installation distances need to be re-determined. In this study, a Lamb wave non-contact ultrasonic gas flow meter is used to measure the flow of hydrogen-mixed natural gas in a T-type pipeline. The greater the hydrogen mixing ratio, the higher the flow rate of the branch pipeline, and the shorter the installation distance of the ultrasonic flow meter, for example, 10% at 150D, 20% at 110D, and 30% at 20D. The time-difference method with high accuracy and broad applicability is used to calculate the flow rates of COMSOL simulated values. The errors between COMSOL simulation and theoretical flow rates at the shortest installation distance downstream do not exceed 3%. The errors at the position where the mixing uniformity is 80% are significantly higher than those at the shortest installation distance, and the maximum error is about 7.7%. The COMSOL simulation results show the feasibility and accuracy of ultrasonic gas flow metering of hydrogen-mixed natural gas

    Design of a High-Gap Plant Protection Machine (HGPM) with Stepless Variable Speed and Power Adjustable Function

    No full text
    The passing performance and driving stability performance of HGPM in an unstructured environment will directly affect the quality of HGPM operation. This paper designs an HGPM power chassis transmission system in order to address the problem of poor adaptability of existing plant protection machines to complex working conditions in the field, especially in the middle and late stage of plant protection operation of tall crops, which cannot pass smoothly due to the obstruction of vision and special road conditions resulting in insufficient traction of the whole machine. The system is theoretically analyzed based on hydrostatic transmission and a time-sharing four-wheel drive splitter; then, based on Solidworks and RecurDyn software, the HGPM is modeled in three dimensions, and the dynamic simulation of working conditions such as climbing, crossing the ridge, and opening the road during field operation is carried out. The simulation results show that the 2H mode can climb over a slope with an angle in the range of 0βˆ’25Β° and a ridge with height in the range of 0βˆ’100 mm, the 4H mode can climb over a slope with an angle in the range of 0βˆ’35Β° and a ridge with height in the range of 0βˆ’320 mm, with relatively stable body speed and the wheel rotation angular speed converging faster under the open road condition. Finally, prototype performance tests were conducted. The test results show that 4H mode can smoothly pass the ridge with a ridge height of 320 mm and a slope of 26Β°, while 2H mode has a sharp drop in speed to 0 after a short fluctuation. 4H mode achieves a more rapid convergence of longitudinal wheel stability compared to 2H mode. The developed chassis drive system of a new type of HGPM meets the design requirements and provides a reference for the dynamic chassis design of HGPM

    Waist-to-Height Ratio and Cardiovascular Risk Factors among Chinese Adults in Beijing

    No full text
    <div><p>Objectives</p><p>To examine whether waist-to-height ratio (WHtR) performed better than, body mass index (BMI) or waist circumference (WC) in relation to hypertension, diabetes, and dyslipidemia among Chinese adults in Beijing.</p><p>Methods</p><p>A total of 5720 adults (2371 men and 3349 nonpregnant women) aged 18 to 79 years were selected from the general population in a cross-sectional study. Data from a standardized questionnaire, physical examination, and blood sample were obtained.</p><p>Results</p><p>The area under curve (AUC) values for WHtR (0.661–0.773) were significantly higher than those for BMI for all outcomes in both sexes, except that WHtR and BMI had similar AUCs for dyslipidemia in men. The AUCs for WHtR were significantly higher than those for WC with respect to hypertension in both sexes, and to diabetes in women. AUCs for the relationships between anthropometric indices and the three outcomes were larger in women than in men, and tended to decrease with age. Optimal cutoffs for WHtR were 0.51–0.53 and 0.48–0.50 in men and women, respectively. With regard to the current Chinese criteria for BMI (β‰₯24 kg/m<sup>2</sup>), WC (β‰₯90 cm for men, and β‰₯85 cm for women), and the recommended cutoff of WHtR (β‰₯0.5), WHtR yielded the greatest odds ratio for hypertension and diabetes in both sexes, and dyslipidemia in women. BMI had the highest odds ratio for dyslipidemia in men. The odds ratios of anthropometric indices for hypertension and diabetes, but not for dyslipidemia, were higher in women than in men. The association between anthropometric indices and the three outcomes decreased with age.</p><p>Conclusion</p><p>WHtR performed better than BMI and WC for the association with hypertension and diabetes. More studies should be conducted to explore the age differences in the relationships between obesity indices and cardiovascular risk factors.</p></div

    Estimates of ROC curve analyses of anthropometric indices for cardiovascular risk factors.

    No full text
    <p>*P<0.05, Compared to BMI.</p>†<p>P<0.05, Compared to WC.</p><p>ROC, receiver operating characteristics; AUC, area under the curve; BMI, body mass index; WC, waist circumference; WHtR, waist-to-height ratio.</p

    Descriptive statistics by sex among adults aged 18–79 years.

    No full text
    <p>BMI, body mass index; WC, waist circumference; WHtR, waist-to-height ratio; SBP, systolic blood pressure; DBP, diastolic blood pressure; FG, fasting glucose; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglycerides.</p
    corecore